Quite a few receptor-mediated events present the phenomenon of desensitization, which implies that continued or repeated administration of the drug provides a progressively more compact result. Amongst the sophisticated mechanisms included are conversion of your receptors to the refractory (unresponsive) state within the existence of the agonist, in order that https://gregorywchmr.blogars.com/27250687/manual-article-review-is-required-for-this-article